Anti-Infliximab Antibody - Medical Algorithm

Are you evaluating a patient who is receiving infliximab?

Yes

Is the patient requiring escalating doses to achieve the same clinical effect?

Yes

Is the duration of effect from a dose much shorter than that seen previously?

Yes

Has the patient failed to respond to therapy?

Yes

Are serum levels of infliximab undetectable or greatly reduced shortly after a dose?

Yes

Does the patient have a history of anti-mouse antibodies?

Yes

Is the patient receiving little or no immunosuppression?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Number of findings that suggest formation of anti-infliximab antibodies

Number of risk factors for forming anti-infliximab antibodies

Should the patient be screened for antibodies to infliximab?

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
- Infusion of Infliximab | Predicting a Reaction in Pediatric Patients

Therapy

Drug Interactions
- Immune Reconstitution Inflammatory Syndrome (IRIS)

Monitoring

Response To Therapy
- Immune Reconstitution Inflammatory Syndrome (IRIS)
Adverse Effects
Complication Detection
- Contraindications for Use of Infliximab

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10

When to Suspect the Formation of Anti-Infliximab Antibodies in a Patient

Purpose: To evaluate a patient receiving infliximab for findings that suggest development of anti-infliximab antibodies.

Evaluation

Results

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MedicalAlgorithms.com APIs

Power Your Solutions with 5,000+ Automated Medical Analytics

Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Therapy

Monitoring

Specialty

Objective

ICD-10