Criteria for Diagnosis of Invasive Aspergillosis

Temperature on admission to the hospital

White blood cell count

Neutrophils in the peripheral blood differential (enter from 0 to 100)

• a history of recent therapy with cytotoxic agent(s) for leukemia or other condition?

• a history of recent glucocorticoid therapy equivalent to 20+ mg prednisone per day?

• an immunodeficiency state?

• an absolute neutropenia (< 500 per µL) for > 30 days?

• 2 or more febrile episodes of unknown source?

• a febrile episode of unknown source lasting for 2 weeks or more?

• fever for 2 weeks or more while receiving appropriate antibiotic therapy?

• lung rales without fluid overload?

• presence of a nasal eschar, ulcer or discharge with epistaxis?

• sinus tenderness?

• pleuritic chest pain?

• an infiltrate first seen after hospital day 14?

• a pulmonary infiltrate in 2 or more lobes?

• lung nodules or cavities?