Management of Chemotherapy Induced Diarrhea

Purpose: To manage chemotherapy-induced diarrhea in a patient receiving irinotecan, fluorouracil and leucovorin (IFL).

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Evaluation

Are you evaluating a patient with chemotherapy-induced diarrhea associated with IFL therapy?

Yes

White blood cell count

Percent neutrophils in the peripheral blood differential (enter from 0 to 100)

Does the patient have a fever?

Yes

Is the person receiving radiation therapy?

Yes

Select the appropriate answer to indicate the degree of diarrhea

Level of diarrhea

Results

Please fill out required fields.

Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Absolute neutrophil count

Should the chemotherapy doses be withheld until after the symptoms have resolved?

The patient can be initially treated as an

The diarrhea should be initially treated with

Should the patient receive fluoroquinolone therapy?

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Clinical Diagnosis, Including Family History For Genetics
- Daily Gut Score of Blijlevens et al for Gastrointestinal Toxicity Associated with Cancer Therapy
- Severe Long-Term Dysphagia Following Radiation Therapy for Head & Neck Cancer
Criteria For Diagnosis
- Criteria for Complicated & Uncomplicated Chemotherapy-Induced Diarrhea
Severity, Prognosis, Stage

Therapy

Prevention
- Recommendations for Prevention of Chronic Radiation Enteritis
Interventional Radiology
- Severe Long-Term Dysphagia Following Radiation Therapy for Head & Neck Cancer
- Risk Factors for Severe Long-Term Dysphagia Following Radiation Therapy for Head & Neck Cancer

Monitoring

Response To Therapy
- Severe Long-Term Dysphagia Following Radiation Therapy for Head & Neck Cancer
- Risk Factors for Severe Long-Term Dysphagia Following Radiation Therapy for Head & Neck Cancer
Adverse Effects

Specialty

Hematology Oncology
Gastroenterology
Pharmacology, clinical

Objective

complications
prevention

ICD-10

K52.1 - Toxic gastroenteritis and colitis
T45.1 - Poisoning, antineoplastic and immunosuppressive drugs

Info

Purpose: To manage chemotherapy-induced diarrhea in a patient receiving irinotecan, fluorouracil and leucovorin (IFL).

Specialty: Hematology Oncology, Gastroenterology, Pharmacology, clinical

Objective: complications, prevention

ICD-10: K52.1, T45.1,

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