Hepatotoxicity Acute Iron Poisoning | Medical Algorithm

Are you evaluating a patient with acute iron intoxication?

Yes

Number of hours after the ingestion that the patient presented to the hospital

Estimated dose of elemental iron ingested

Body weight

Does the patient admit to taking a large number of iron pills?

Yes

Does a flat plate of the abdomen show iron tablets in the gastrointestinal tract?

Yes

Does the patient have evidence of gastrointestinal bleeding or iron toxicity?

Yes

Does the patient show?

• progressive hepatomegaly?

Yes

• jaundice?

Yes

• coma?

Yes

Peak serum iron concentration

Upper limit of the normal reference range for serum iron

Select an appropriate answer for each finding

Liver function tests

Liver biopsy

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Data complete?

Evaluation appropriate?

Intake of elemental iron per kg body weight

Ratio of peak serum iron concentration to the upper limit of the normal reference range

Number of additional reasons to suspect a significant exposure

Is the patient at risk for hepatoxicity based on intake estimates or the serum iron concentration?

Number of findings suggesting hepatotoxicity is already significant

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Interpretation and Description

References

Next Steps in Evaluation

Severity, Prognosis, Stage
- Clinical Stages of Iron Intoxication

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10

Criteria for Hepatotoxicity Associated with Acute Iron Poisoning

Purpose: To evaluate a patient with acute iron intoxication for hepatoxicity.

Evaluation

Results

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Specialty

Objective

ICD-10