Risk Factors for Hepatocellular Injury in Pediatric Acetaminophen Overdose

Purpose: To identify a pediatric patient at risk for hepatocellular injury after an acetaminophen overdose.

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Evaluation

Are you evaluating a pediatric patient who has taken an overdose of acetaminophen?

Yes

Age of the patient

years

Weight of the patient

Number of hours since the acetaminophen dose was ingested

Acetaminophen dose

Was the overdose intentional?

Yes

Is the patient Caucasian?

Yes

Results

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Results Interpretation and Description References Next Steps

Data complete?

Evaluation appropriate?

Cumulative product for the risk factor odd ratios

The risk of hepatocellular injury in the patient is

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Interpretation and Description

References

Next Steps in Evaluation

Diagnosis

Risk Factors
Clinical Diagnosis, Including Family History For Genetics
- Clinical Findings of Opioid Toxicity in Patient Treated for Pain
- Pseudosepsis Syndrome in Salicylate Intoxication
Laboratory Tests
- Acetaminophen Serum Levels (Rumach-Matthew Nomogram)

Therapy

Selection
- When to Suspect Salicylate Intoxication in an Elderly Patient
- Treatment Line for Patient at Increased Risk for Acetaminophen (Paracetamol) Toxicity
Dosage Calculations
- Clinical Findings of Opioid Toxicity in Patient Treated for Pain
Prevention
- Pulmonary Syndromes Complicating Salicylate Therapy

Monitoring

Adverse Effects
Overdose And Reversal
- When to Suspect Salicylate Intoxication in an Elderly Patient

Specialty

Toxicology
Emergency Medicine
Critical Care

Objective

risk factors
selection

ICD-10

T39.1 - Poisoning, 4-aminophenol derivatives

Info

Purpose: To identify a pediatric patient at risk for hepatocellular injury after an acetaminophen overdose.

Specialty: Toxicology, Emergency Medicine, Critical Care

Objective: risk factors, selection

ICD-10: T39.1,

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